Methicillin-resistant Staph Aureus FAQ (adapted from CDC)

MRSA BUNDLE FOR ORLANDO HEALTH (2019-2020) - below

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What is MRSA?

  • MRSA stands for Methicillin-resistant Staphylococcus aureus, which is a strain of Staphylococcus aureus that has acquired resistance to several antibiotics. 

  • Staph aureus can be part of the normal bacterial flora and typically colonizes on the skin and in the nose.

  • MRSA most commonly causes skin infection, which presents as swelling, redness, warmth, and pain in the affected area.

  • If left untreated, MRSA can infect the bloodstream causing sepsis leading to more severe complications.

    • Although MRSA is not an immediately life-threatening condition, anyone who suspects MRSA infection should seek treatment urgently to prevent further complications from the infection.

    • MRSA can be spread in the community through contact with contaminated objects, skin injuries, or contact with infected individuals.

What are the risk factors associated with MRSA?

  • Prolonged stay at a hospital

  • Recent surgery

  • Implanted medical devices

  • Skin injury

  • Previous MRSA infection

  • Family history of MRSA infection

What are the recommended guidelines for preventing MRSA?

  • Following and maintaining contact precautions for known MRSA infections are the most effective means of preventing transmission.

What steps can patients and team members take to prevent MRSA?

  • Maintaining proper hand and body hygiene is the most important means of preventing MRSA infection.

  • All individuals interacting with the patient should use personal protective equipment (PPE), which includes donning a gown and gloves.

How do I diagnose the condition? What other things are in the differential diagnosis?

  • Common signs and symptoms of MRSA infection include:

    • Skin swelling

    • Warmth, redness, pain in the affected area

    • Fever

    • Leukocytosis

  • For the differential diagnosis of a skin infection, other bacteria can present similarly. These include primarily other Staphylococcus and Streptococcus species.

How do I treat/manage the clinical condition?

  • Treatment of MRSA infections often requires inpatient admission with long-term IV antibiotic therapy such as Vancomycin or Daptomycin.

  • Avoid direct skin-to-skin contact with others is essential for preventing the spread of MRSA.

What complications are associated with MRSA?

  • The most critical and life-threatening complications of MRSA are bacteremia and sepsis.

Who else can I call for more information?

  • Hospital Epidemiologist – Asim Jani, MD, MPH : (407) 230-9015 (24/7 cell)

  • Director, Infection Prevention – Eve Early MT, MA, CIC - (678) 789-6461

  • Infection Prevention (hospital-specific and/or on call): PerfectServe

  • Director, Occupational Health – Ken Michaels, DO: (321) 841-8056

What are some additional resources to learn more (online links and literature)?

FAQs:

Videos and Podcasts:

Graphs:

Journals and Articles:

UpToDate: